Separate from the risk due to caramel coloring, CSPI has been urging the FDA to ban synthetic food colorings, such as Yellow 5 and Red 40. Those dyes cause hyperactivity and other behavioral problems in children, and Red 3 and Yellows 5 and 6 pose cancer risks, according to CSPI. The FDA is holding a Food Advisory Committee review of that issue on March 30–31.
Over the years, CSPI's efforts have resulted in reductions in the use of, labeling requirements, or limits on Violet No. 1, sodium nitrite and sodium nitrate, sulfites, partially hydrogenated vegetable oils, salt, and olestra.